Search on: HD1 PROTEIN, 500-KDA 
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Descriptor English:   Plectin 
Descriptor Spanish:   Plectina 
Descriptor Portuguese:   Plectina 
Synonyms English:   500-kDa HD1 Protein
Hemidesmosomal Protein HD1
500 kDa HD1 Protein
HD1 Protein, 500-kDa
HD1, Hemidesmosomal Protein  
Tree Number:   D12.776.220.790.750
D12.776.744.736
Definition English:   A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C. 
History Note English:   2006(1982) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50941 
Unique Identifier:   D051190 

Occurrence in VHL: 		 

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